Gerhard Hummer
Department of Theoretical Biophysics, Max Planck Institute of Biophysics,
60438 Frankfurt am Main, Germany
(Email: Gerhard.Hummer@biophys.mpg.de)
We have used molecular dynamics simulations and statistical mechanical
theory to characterize the molecular mechanisms of biological energy
transduction processes in the proton pumps cytochrome c oxidase and
complex I, and in the coupled rotary motors of FoF1-ATP synthase. These
machines exploit solvation eects and protein conformational changes for
the ecient interconversion of chemical, electrostatic, and mechanical
energy.