Chargé de recherche CNRS (CRCN)

ENS – Département de chimie
24 rue Lhomond, 75005 Paris

Phone: +33 144323327
Office: E033c

Short bio

Sergii Rudiuk graduated in 2005 from Chemistry Department of Kiev University in Ukraine where he performed his master research in organic chemistry. After defending his PhD thesis in 2009 in Chemistry department of Toulouse University (France), he performed several research internships and postdoctoral stays in Japan, Germany and France, where he acquired a strong background in soft matter, molecular biology and nanobiotechnology. In 2013 Sergii Rudiuk obtained permanent CNRS position in the Chemistry Department of Ecole Normale Supérieure in Paris, and is continuing performing interdisciplinary research at the interface of chemistry, physics and biology. His present research interests focus mainly on DNA-protein conjugates, DNA nanotechnology and development of new methods for Atomic Force Microscopy.

Education and professional experience

Since 2013 – CNRS researcher

2011 – 2013: postdoctoral position in the Department of Chemistry, Ecole Normale Supérieure (ENS), in the team of Pr. Damien Baigl
Preparation of DNA-protein conjugates and their applications for bio- and nano- technology

2010 – 2011: postdoctoral position in the Department of Chemistry, Ecole Normale Supérieure (ENS), in the team of Dr. Christophe Tribet
Interfacial aggregation of therapeutic antibodies

2009 – 2010: postdoctoral position in Yoshikawa laboratory, Kyoto University, Japan
    – Enhancement of surfactants-induced DNA compaction by negatively charged nanoparticles
    – Selective photocontrol of genes expression

2005 – 2009: PhD research in IMRCP laboratory, Paul Sabatier University, Toulouse, France (supervision of Dr. Isabelle Rico-Lattes )
Influence of DNA complexation with cationic surfactants, polymers and lipids on its photooxidative damage

2000 – 2005: Master 2 degree with honours, Taras Shevchenko National University, Kiev, Ukraine (supervision of Dr. Zoia Voitenko)
major : “Organic chemistry” and “Macromolecular Chemistry”

Research interests

      • DNA-protein conjugates
      • DNA nanogels
      • Photocontrol

Full list of publications

      • Zhou, L., P. Retailleau, M. Morel, S. Rudiuk, D. Baigl
        Photoswitchable fluorescent crystals obtained by the photoreversible co-assembly of a nucleobase and an azobenzene intercalator
        J. Am. Chem. Soc. 2019, 10.1021/jacs.9b02836.
      • Vialetto, M. Anyfantakis, S. Rudiuk, M. Morel, D. Baigl
        Photoswitchable Dissipative Two-Dimensional Colloidal Crystals
        Angew. Chem. Int. Ed. 2019, 10.1002/anie.201904093.
      • Hayakawa, M., J. Vialetto, M. Anyfantakis, M. Takinoue, S. Rudiuk, M. Morel, D. Baigl
        Effect of Moderate Magnetic Fields on the Surface Tension of Aqueous Liquids: a Reliable Assessment
        RSC Adv. 2019, 9, 10030–10033.
      • Evenou, P., J. Rossignol, G. Pembouong, A. Gothland, D. Colesnic, R. Barbeyron, S. Rudiuk, A.-G. Marcelin, M. Ménand, D. Baigl, V. Calvez, L. Bouteiller, M. Sollogoub
        Bridging β‐Cyclodextrin Prevents Self‐Inclusion, Promotes Supramolecular Polymerization, and Promotes Cooperative Interaction with Nucleic Acids
        Angew. Chem. Int. Ed. 2018, 57, 7753-7758.
      • Vialetto, J., M. Hayakawa, N. Kavokine, M. Takinoue, S. N. Varanakkottu, S. Rudiuk, M. Anyfantakis, M. Morel, D. Baigl
        Magnetic actuation of discrete liquid entities with a deformable paramagnetic liquid substrate
        Angew. Chem. Int. Ed. 2017, 56, 16565-16570.
      • Anyfantakis, M., S. N. Varanakkottu, S. Rudiuk, M. Morel, D. Baigl
        Evaporative Optical Marangoni Assembly (eOMA): tailoring the three-dimensional morphology of individual deposits of nanoparticles from sessile drops
        ACS Appl. Mater. Interfaces 2017, 9 (42), 37435–37445.
      • Zhou, L., M. Morel, S. Rudiuk, D. Baigl
        Intramolecularly Protein-Crosslinked DNA Gels: new biohybrid nanomaterials with controllable size and catalytic activity
        Small 2017, 13(28), 1700706.
      • Devineau, S., M. Anyfantakis, L. Marichal, L. Kiger, M. Morel, S. Rudiuk, D. Baigl
        Protein adsorption and reorganization on nanoparticles probed by the coffee-ring effect: application to single point mutation detection
        J. Am. Chem. Soc. 2016, 138, 11623−11632.
      • Kavokine, N., M. Anyfantakis, M. Morel, S. Rudiuk, T. Bickel, D. Baigl
        Optical transport of liquid marbles in and against surface flows
        Angew. Chem. Int. Ed. 2016, 55, 11183 –11187.
      • Lee Tin Wah, J., C. David, S. Rudiuk, D. Baigl, A. Estevez-Torres
        Observing and controlling the folding pathway of DNA origami at the nanoscale
        ACS Nano 2016, 10(2), 1978–1987.
      • Bergen, A., S. Rudiuk, M. Morel, T. Le Saux, H. Ihmels, D. Baigl
        Photodependent melting of unmodified DNA using a photosensitive intercalator: a new and generic tool for photoreversible assembly of
        DNA nanostructures at constant temperature

        Nano Lett. 2016, 16 (1), 773–780.
      • Varanakkottu, S. N., M. Anyfantakis, M. Morel, S. Rudiuk, D. Baigl
        Light-directed particle patterning by evaporative optical Marangoni assembly
        Nano Lett. 2016, 16 (1), 644–650.
      • Nurdin, L., A. Venancio-Marques, S. Rudiuk, M. Morel, D. Baigl
        High-throughput photocontrol of water drop generation, fusion, and mixing in a dual flow-focusing microfluidic device
        C. R. Chimie 2016, accepted, DOI : 10.1016/j.crci.2015.07.012.
      • Anyfantakis, M., Z. Geng, M. Morel, S. Rudiuk, D. Baigl
        Modulation of the coffee-ring effect in particle/surfactant mixtures: the importance of particle-interface interactions
        Langmuir 2015, 31, 4113−4120.
      • Venancio-Marques A., A. Bergen, C. Rossi-Gendron, Rudiuk S., D. Baigl
        Photosensitive polyamines for high-performance photocontrol of DNA higher-order structure
        ACS Nano 2014, 8, 3654–3663.
      • Mani, K. N., Rudiuk S., D. Baigl
        Spatially controlled DNA unzipping by microfluidic interface positioning on a molecule perpendicular to a multicomponent flow
        Chem. Commun. 2013, 49 (61), 6858 – 6860.
      • Rudiuk S., A. Venancio-Marques, G. Hallais, D. Baigl
        Preparation of one- to four-branch silver nanostructures of various sizes by metallization of hybrid DNA-protein assemblies
        Soft Matter 2013, 9, 9146-9152.
      • Rudiuk S., A. Venancio-Marques, D. Baigl
        Enhancement and modulation of enzymatic activity through higher-order structural changes of giant DNA-protein multibranch conjugates
        Angew. Chem. Int. Ed. 2012, 51, 12694 –12698.
      • Diguet A., M. Yanagisawa, Y.-J. Liu, E. Brun, S. Abadie, S. Rudiuk, D. Baigl
        UV-Induced Bursting of Cell-Sized Multi-Component Lipid Vesicles in a Photosensitive Surfactant Solution
        J. Am. Chem. Soc. 2012, 134, 4898−4904.
      • Rudiuk S., L. Cohen-Tannoudji, S. Huille, C. Tribet
        Importance of the dynamics of adsorption and of a transient interfacial stress on the formation of aggregates of IgG antibodies
        Soft Matter 2012, 8, 2651-2661.
      • Schiessel H., M. D. Correa-Rodríguez, S. Rudiuk, D. Baigl, K. Yoshikawa
        Theory of DNA-cationic micelle complexation
        Soft Matter 2012, 8, 9406-9411.
      • Liu Y.-J., A. Pallier, J. Sun, S. Rudiuk, D. Baigl, M. Piel, E. Marie, C. Tribet
        Non-monotonous variation of the LCST of light-responsive, amphiphilic poly(NIPAM) derivatives
        Soft Matter 2012, 8, 8446-8455.
      • Rudiuk S., K. Yoshikawa, D. Baigl
        Enhancement of DNA Compaction by Negatively Charged Nanoparticles. Effect of Nanoparticle Size and Surfactant Chain Length
        J. Colloid Interface Sci, 2012, 368, 372-377.
      • Rudiuk S., T. Hara, H. Saito, K. Yoshikawa, D. Baigl
        Light-Regulated mRNA Condensation by a Photosensitive Surfactant Works as a Series Photoswitch of Translation Activity in the Presence of Small RNAs
        Biomacromolecules 2011, 12, 3945−3951.
      • Rudiuk S., K. Yoshikawa, D. Baigl
        Enhancement of DNA Compaction by Negatively Charged Nanoparticles. Application to Reversible Photocontrol of DNA Higher-Order Structure
        Soft Matter 2011, 7, 5854-5860.
      • Rudiuk S., S. Franceschi-Messant, N. Chouini-Lalanne, E. Perez, I. Rico-Lattes
        DNA photooxidative damage hazard in transfection complexes
        Photochem. Photobiol. 2011, 87, 103-108.
      • Rudiuk S., M. Delample, S. Franceschi-Messant, N. Chouini-Lalanne, E. Perez, J.-C. Garrigues, I. Rico-Lattes
        Spontaneous vesicle formation by caffeate ion-pair surfactants: antioxidant properties and application to DNA protection
        J. Disp. Sci. Tech. 2010, 31, 384–391.
      • Rudiuk S., S. Franceschi-Messant, N. Chouini-Lalanne, E. Perez, I. Rico-Lattes
        Modulation of photo-oxidative DNA damage by cationic surfactant complexation
        Langmuir 2008, 24, 8452-8457.
      • Rudiuk S.A.; Voitenko, Z.V.; Riabov, S.V.; Roshal, A.D.
        Molecular complexes of 4,10-dihydrothieno[3′,2′:5,6]pyrimido[2,1-a]isoindol-4-ones with β-cyclodextrin
        J. Incl. Phenom. Macrocycl. Chem. 2007, 57(1-4), 415-417.