Assistant professor, École Normale Supérieure
ENS – Département de chimie
24 rue Lhomond, 75005 Paris
Email: mathilde.lepoitevin@ens.psl.eu
Phone: +33 144322460
Office: E024
Short bio
- Since September 2018, Mathilde Lepoitevin is an assistant professor in Chemistry at Ecole Normale Superieure, in the Porous Materials Institute of Paris.
During her bachelor’s she began to work on proteins interaction with materials. Before finishing that degree, she was admitted to the Materials for Energy Storage and Conversion (MESC) Master with a scholarship. While working on her master’s thesis, she was granted a PhD fellowship by Montpellier University (Fr), under the supervision of Dr. Balme and Dr. Bechelany. Her PhD work consisted in developing and designing single solid state nanopores to mimic biological channels and to investigate either bio-macromolecules translocation or to functionalize the nanopore to mimic stimuli-dependent ion channels. During her PhD, she was the recipient of a travel grant from the “Chaire Total” for a short-term stay collaboration work with Dr. Dumee group at Deakin University (Australia).
In January 2017, she started working as a postdoctoral research fellow, at Brown University (Providence (RI), USA), under the guidance of Pr. D. Stein. There, she developed and demonstrated a new kind of ion source capable of efficiently transferring single amino acid ions from liquid into a mass spectrometer. Her results indicate a feasible path to single-molecule protein sequencing through a combination of a single-ion source and mass spectrometry.
She has co-authored 20 papers in peer-reviewed journals, and her work has been presented in 15 international conferences and 8 invited seminars. She has been the recipient of best PhD award from the “pole chimie Balard” in 2017.
Education and professional experience
- Since 2018, Assistant Professor, Department of Chemistry, École Normale Supérieure, PSL University, Paris, France
- 2017 – 2018: Postdoctoral research associate, with Pr. D. Stein, Brown University, Department of Physics, Providence RI, USA
- 2013 – 2016: PhD with Dr. S. Balme & Dr. M. Bechelany, Institut Européen des Membranes, Université de Montpellier, France
- 2015: Visiting PhD Student, with Dr. L. Dumee, Deakin University, Institute for Frontier Materials, Waurn Ponds VIC, Australia
- 2011 – 2013: MSc Erasmus Mundus, Material for Energy Storage and Conversion
Research interests
- Nanopore, Biosensor, Nano-electrochemistry, Material Science
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Awards and distinctions
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- You can also list the membership to professional organizations (SCF, e.g.)
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Supervised students and post-doctorants
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- Xin MA, Master Chemistry and Life Science, PSL, Nov. 2018 – Nov. 2022
- My-An TRAN, Magistère de Physico-Chimie Moléculaire, Université Paris-Saclay Feb. 2019 – July 2019
- Andrea FELLONI, M.S. in Nanostructured Materials Engineering, Politecnico di Milano, March 2019 – Feb 2020
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Teaching
Significant publications
- Bush, Joseph, William Maulbetsch, Mathilde Lepoitevin, Benjamin Wiener, Mirna Mihovilovic Skanata, Wooyoung Moon, Cole Pruitt, and Derek Stein. « The nanopore mass spectrometer. » Review of Scientific Instruments 88, no. 11 (2017): 113307
- Lepoitevin, Mathilde, Maguy Jaber, Régis Guégan, Jean-Marc Janot, Philippe Dejardin, Francois Henn, and Sébastien Balme. « BSA and lysozyme adsorption on homoionic montmorillonite: Influence of the interlayer cation. » Applied Clay Science 95 (2014): 396-402.
- Lepoitevin, Mathilde, Tianji Ma, Mikhael Bechelany, Jean-Marc Janot, and Sebastien Balme. « Functionalization of single solid state nanopores to mimic biological ion channels: A review. » Advances in colloid and interface science 250 (2017): 195-213.
- Lepoitevin, Mathilde, Gael Nguyen, Mikhael Bechelany, Emmanuel Balanzat, Jean-Marc Janot, and Sebastien Balme. « Combining a sensor and a pH-gated nanopore based on an avidin–biotin system. » Chemical Communications 51, no. 27 (2015): 5994-5997.
Publications
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