Eric LABBE

Professeur Sorbonne Université

ENS – Département de chimie
24 rue Lhomond, 75005 Paris

Email: eric.labbe@ens.psl.eu
Phone: 0144322433
Office: E010

Short bio

Eric Labbé is an analytical electrochemist interested in the understanding of reactivity and transport issues related to biological molecules. He started studying  electrosynthetic and electrocatalytic sequences in the group of Jacques Périchon at Université Paris Est (UPEC) until 2005. Since 2006, he is Professor at Sorbonne Université (SU) and his research topics focus on the exploration of drug metabolism as well as biomolecule distribution accross lipid membranes, through the electrochemical switching ON/OFF of fluorescent probes.

 

Education and professional experience

  • Since 2006         Professor, Sorbonne Université
  • 1992 – 2005      Maître de Conférences, IUFM de Créteil
  • 1991 – 1992      Postdoc, Université Pierre et Marie Curie
  • 1988 – 1991      PhD, Université Pierre et Marie Curie

 

Research interests

  • Keywords : electrochemistry ; mechanisms ; metabolism ; transport

The journey of a biomolecule (drug, peptide,…) throughout a living organism from its generation -or administration- to its elimination encompasses namely metabolic processes and transport steps accross barriers. Eric Labbé is interested in delineating the metabolism of such molecules and the dynamics of their passage through lipid membranes, which are central considerations for both the identification of the active metabolites and the evaluation of their bio-availability. Within this topic, his research concerns the development of electrochemically switchable dual redox/fluorescent probes.

 

Teaching

 

Significant publications

 

  1.  “The Fundamental Input of Analytical Electrochemistry in the Determination of Intermediates and Reaction Mechanisms in Electrosynthetic Processes.” ChemElectroChem Minireview,  2019, 6, 4118.
  2. “Redox switchable rhodamine-ferrocene dyad: Exploring imaging possibilities in cells”  Electrochemistry Communications, 2018, 97,  46.
  3. “Selective Electrochemical Bleaching of the Outer Leaflet of Fluorescently Labelled Giant Liposomes”  Chem. Eur.J., 2017, 23, 6781
  4. “Electrochemical Behavior of Plutonium in n-TriButylPhosphate”  Dalton Trans., 2017, 46, 4943.
  5. “Monitoring and Quantifying the Passive Transport of Molecules Through Patch–Clamp Suspended Real and Model Cell Membranes “  Angew. Chem. Int Ed. , 2014, 53, 3192.  Key Scientific Article  of the Global Medical Discovery newsfeed.

 

Publications accessible from Open Access platforms   /

 

 

Publications ( full record)

  • Publons : click here
  • ORCID : click here
  • Google Scholar : click here
  • ResearchGate : click here

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2019

Eric Labbe

A Fluorescent False Neurotransmitter as a Dual Electrofluorescent Probe for Secretory Cell Models Article de journal

ChemPlusChem, 2019, ISSN: 2192-6506.

Liens

Eric Labbe

A Fluorescent False Neurotransmitter as a Dual Electrofluorescent Probe for Secretory Cell Models Article de journal

ChemPlusChem, 2019, ISSN: 2192-6506.

Liens

Eric Labbe

Fundamental Input of Analytical Electrochemistry in the Determination of Intermediates and Reaction Mechanisms in Electrosynthetic Processes Article de journal

ChemElectroChem, 2019, ISSN: 2196-0216.

Liens

Eric Labbe

Fundamental Input of Analytical Electrochemistry in the Determination of Intermediates and Reaction Mechanisms in Electrosynthetic Processes Article de journal

ChemElectroChem, 2019, ISSN: 2196-0216.

Liens

2017

Mohamed Ali Bahri; Alexandre Ruas; Eric Labbé; Philippe Moisy

Electrochemical Characterization of Plutonium in n-Tributyl Phosphate Article de journal

Dalton Transactions, p. 4943-4949, 2017.

Mohamed Ali Bahri; Alexandre Ruas; Eric Labbé; Philippe Moisy

Electrochemical Characterization of Plutonium in n-Tributyl Phosphate Article de journal

Dalton Transactions, p. 4943-4949, 2017.

Olivier Buriez; Ana Isabel Perez Jimenez; Lylian Challier; Eric Aït-Yahiatène; Jerome Delacotte; Eric Labbe

Selective Electrochemical Bleaching of the Outer Leaflet of Fluorescently Labelled Giant Liposomes Article de journal

Chemistry A European Journal, 23 , p. 6781-6787, 2017.

2015

Guillaume Longatte; Han-Yi Fu; Olivier Buriez; Eric Labbé; Francis-André Wollman; Christian Amatore; Fabrice Rappaport; Manon Guille-Collignon; Frédéric Lemaître

Evaluation of photosynthetic electrons derivation by exogenous redox mediators Article de journal

Biophysical Chemistry, 205 , p. 1-8, 2015.

Guillaume Longatte; Han-Yi Fu; Olivier Buriez; Eric Labbé; Francis-André Wollman; Christian Amatore; Fabrice Rappaport; Manon Guille-Collignon; Frédéric Lemaître

Evaluation of photosynthetic electrons derivation by exogenous redox mediators Article de journal

Biophysical Chemistry, 205 , p. 1-8, 2015.

Hui Zhi Shirley Lee; Olivier Buriez; François Chau; Eric Labbé; Rakesh Ganguly; Christian Amatore; Gérard Jaouen; Anne Vessières; Weng Kee Leong; Siden Top

Synthesis, Characterization, and Biological Properties of Osmium-Based Tamoxifen Derivatives – Comparison with Their Homologues in the Iron and Ruthenium Series Article de journal

European Journal of Inorganic Chemistry, p. n/a, 2015.

Hui Zhi Shirley Lee; Olivier Buriez; François Chau; Eric Labbé; Rakesh Ganguly; Christian Amatore; Gérard Jaouen; Anne Vessières; Weng Kee Leong; Siden Top

Synthesis, Characterization, and Biological Properties of Osmium-Based Tamoxifen Derivatives – Comparison with Their Homologues in the Iron and Ruthenium Series Article de journal

European Journal of Inorganic Chemistry, p. n/a, 2015.

Ana Isabel Perez Jimenez; Lylian Challier; Margherita Di Pisa; Manon Guille-Collignon; Frédéric Lemaître; Solange Lavielle; Christelle Mansuy; Christian Amatore; Eric Labbé; Olivier Buriez

Three-electrode analytical and preparative electrochemistry in micro-volume hanging droplets Article de journal

Electrochemistry Communications, 54 (0), p. 41-45, 2015.

Ana Isabel Perez Jimenez; Lylian Challier; Margherita Di Pisa; Manon Guille-Collignon; Frédéric Lemaître; Solange Lavielle; Christelle Mansuy; Christian Amatore; Eric Labbé; Olivier Buriez

Three-electrode analytical and preparative electrochemistry in micro-volume hanging droplets Article de journal

Electrochemistry Communications, 54 (0), p. 41-45, 2015.

2014

Eric Labbe

Advances in Organometallic Chemistry and Catalysis : The Silver/Gold Jubilee International Conference on Organometallic Chemistry Celebratory Book, First Edition. Edited by Armando J. L. Pombeiro. Livre

2014.

Liens

Eric Labbe

Advances in Organometallic Chemistry and Catalysis : The Silver/Gold Jubilee International Conference on Organometallic Chemistry Celebratory Book, First Edition. Edited by Armando J. L. Pombeiro. Livre

2014.

Liens

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