Pascal PLAZA

Directeur de recherche – CNRS

ENS – Département de chimie
24 rue Lhomond, 75005 Paris

Phone: 01 44 32 24 14
Office: E123
ORCID: 0000-0002-8021-4521

Research interests

Photoactives Proteins; Flavoproteins; Reversibly Switchable Fluorescent Proteins;
Ultrafast Time-Resolved Spectroscopy;  Photophysics; Photochemical Processes;
Electron and Proton Transfer;
See more details here.



Master of chemistry at Sorbonne Université: « Primary Photoreactivity of Molecular and Macromolecular Systems in Condensed Phase » module of UE 5C206 – Ultrafast Dynamics of Reactive Species.



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Ultrafast Oxidation of a Tyrosine by Proton-Coupled Electron Transfer Promotes Light Activation of an Animal-like Cryptochrome Article de journal

Fabien Lacombat; Agathe Espagne; Nadia Dozova; Pascal Plaza; Pavel Müller; Klaus Brettel; Sophie Franz-Badur; Lars-Oliver Essen

Journal of the American Chemical Society, 141 (34), p. 13394-13409, 2019, ISSN: 0002-7863.

Résumé | Liens

Ultrafast photoinduced flavin dynamics in the unusual active site of the tRNA methyltransferase TrmFO Article de journal

N Dozova; F Lacombat; C Bou-Nader; D Hamdane; P Plaza

Physical Chemistry Chemical Physics, 21 (17), p. 8743-8756, 2019, ISSN: 1463-9076.



A novel diarylethene-based photoswitchable chelator for reversible release and capture of Ca2+ in aqueous media Article de journal

N Dozova; G Pousse; B Barnych; J -M Mallet; J Cossy; B Valeur; P Plaza

Journal of Photochemistry and Photobiology A: Chemistry, 360 , p. 181–187, 2018.

Résumé | Liens

Delocalized hole transport coupled to sub-ns tryptophanyl deprotonation promotes photoreduction of class II photolyases Article de journal

F Lacombat; A Espagne; N Dozova; P Plaza; E Ignatz; S Kiontke; L O Essen

Physical Chemistry Chemical Physics, 20 (39), p. 25446-25457, 2018, ISSN: 1463-9076.



Loss of Fourth Electron-Transferring Tryptophan in Animal (6-4) Photolyase Impairs DNA Repair Activity in Bacterial Cells Article de journal

J Yamamoto; K Shimizu; T Kanda; Y Hosokawa; S Iwai; P Plaza; P Müller

Biochemistry, 56 (40), p. 5356–5364, 2017.

Résumé | Liens

Photoinduced Chromophore Hydration in the Fluorescent Protein Dreiklang Is Triggered by Ultrafast Excited-State Proton Transfer Coupled to a Low-Frequency Vibration Article de journal

F Lacombat; P Plaza; M -A Plamont; A Espagne

Journal of Physical Chemistry Letters, 8 (7), p. 1489–1495, 2017.

Résumé | Liens

Repair of (6-4) Lesions in DNA by (6-4) Photolyase: 20 Years of Quest for the Photoreaction Mechanism Article de journal

J Yamamoto; P Plaza; K Brettel

Photochemistry and Photobiology, 93 (1), p. 51–66, 2017.

Résumé | Liens

Ultrafast flavin photoreduction in an oxidized animal (6-4) photolyase through an unconventional tryptophan tetrad Article de journal

P R Martin; F Lacombat; A Espagne; N Dozova; P Plaza; J Yamamoto; P Müller; K Brettel; A De La Lande

Physical Chemistry Chemical Physics, 19 (36), p. 24493–24504, 2017.

Résumé | Liens


Excited-state symmetry breaking of linear quadrupolar chromophores: A transient absorption study Article de journal

N Dozova; L Ventelon; G Clermont; M Blanchard-Desce; P Plaza

Chemical Physics Letters, 664 , p. 56–62, 2016.

Résumé | Liens

Ultrafast Dynamics of a Green Fluorescent Protein Chromophore Analogue: Competition between Excited-State Proton Transfer and Torsional Relaxation Article de journal

T Chatterjee; F Lacombat; D Yadav; M Mandal; P Plaza; A Espagne; P K Mandal

Journal of Physical Chemistry B, 120 (36), p. 9716–9722, 2016.

Résumé | Liens


Photo-induced cation translocation in a molecular shuttle based on a calix[4]-biscrown including DCM and DMABN chromophores Article de journal

N Dozova; R Kumar; T Pradhan; F Lacombat; B Valeur; J S Kim; P Plaza

Chemical Communications, 51 (80), p. 14859–14861, 2015.

Résumé | Liens

Real-time monitoring of chromophore isomerization and deprotonation during the photoactivation of the fluorescent protein Dronpa Article de journal

D Yadav; F Lacombat; N Dozova; F Rappaport; P Plaza; A Espagne

Journal of Physical Chemistry B, 119 (6), p. 2404–2414, 2015.

Résumé | Liens


Repair of the (6-4) photoproduct by DNA photolyase requires two photons Article de journal

J Yamamoto; P R Martin; S Iwai; P Plaza; K Brettel

Angewandte Chemie - International Edition, 52 (29), p. 7432–7436, 2013.

Résumé | Liens

Ultrafast carbonyl motion of the photoactive yellow protein chromophore probed by femtosecond circular dichroism Article de journal

L Mendonça; F Hache; P Changenet-Barret; P Plaza; H Chosrowjan; S Taniguchi; Y Imamoto

Journal of the American Chemical Society, 135 (39), p. 14637–14643, 2013.

Résumé | Liens


Photoantenna in two cryptochrome-photolyase proteins from O. tauri: Presence, nature and ultrafast photoinduced dynamics Article de journal

J Brazard; C Ley; F Lacombat; P Plaza; L Mony; M Heijde; G Zabulon; C Bowler

Journal of Photochemistry and Photobiology A: Chemistry, 234 , p. 135–145, 2012.

Résumé | Liens

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