Nicolas BOLIK-COULON

PhD student, École Normale Supérieure
Laboratoire des Biomolécules, UMR7203

ENS – Département de chimie
24 rue Lhomond, 75005 Paris

Email: nicolas.bolik-coulon@ens.psl.eu
Office: ES111

Short bio

Nicolas Bolik-Coulon was an undergrad at the Chemistry department of the École Normale Supérieure, Paris, where he received training in organic, inorganic and physical chemistry and then specialized in biophysics. He joined the Laboratoire des Biomolecules in 2016 for his master thesis under the supervision of Prof. Fabien Ferrage on the characterization of the structural ensemble of a long Intrinsically Disordered Protein (IDP) using Nuclear Magnetic Resonance (NMR). As part of his program, he stayed another year in the lab developing computational tools to analyze high-resolution relaxometry data to characterize the dynamics of proteins over a wide range of timescales (pico- to nanosecond). In 2017-2018, he joined Prof. Wolfgrang Peti at the University of Arizona, Tucson, USA. He started his PhD under the supervision of Prof. Fabien Ferrage in 2018 on the development of tools to characterize the dynamics of protein by NMR.

Education and professional experience

• since 2018               PhD student under the supervision of Prof. Fabien Ferrage, Ecole Normale Supérieure, Paris
• 2019-2021               Co-chair of the Gordon Research Seminar on Computational Aspects of Biomolecular NMR
• 2017-2018               Research Technician in Prof. Wolfgang Peti lab, University of Arizona, USA
• 2016-2017               Internship student under the supervision of Prof. Fabien Ferrage, Ecole Normale Supérieure, Paris
• 2014-2016               Master of Science in Chemistry and Biophysics, with distinction
• 2011-2014               Bachelor of Science in Chemistry, with distinction

Research interests

• Protein dynamics
• Nuclear Magnetic Resonance
• Structural biology

Awards and distinctions

• 2018-2021             PhD fellowship from the École Normale Supérieure, Paris
• 2013-2017              4-year fellowship from the École Normale Supérieure, Paris

Teaching

• Teaching Assistant at the Chemistry Department of the École Normale Supérieure

Significant publications

1. Time-Resolved Protein Side-Chain Motions Unraveled by High-resolution Relaxometry and Molecular Dynamics Simulations, S.F. Cousin, P. Kadeřávek, N. Bolik-Coulon, Y. Gu, C. Charlier, L. Carlier, L. Bruschweiler-Li, T. Marquardsen, J-M Tybrun, R. Bruschweiler, F. Ferrage, J. Am. Chem. Soc., 140, 13456 (2018)

Publications