Assistant professor, École Normale Supérieure

ENS – Département de chimie
24 rue Lhomond, 75005 Paris

Phone: +33 144.322.460
Office: E024

Short bio

    Since September 2018, Mathilde Lepoitevin is an assistant professor in Chemistry at Ecole Normale Superieure, in the Porous Materials Institute of Paris.
    During her bachelor’s she began to work on proteins interaction with materials. Before finishing that degree, she was admitted to the Materials for Energy Storage and Conversion (MESC) Master with a scholarship. While working on her master’s thesis, she was granted a PhD fellowship by Montpellier University (Fr), under the supervision of Dr. Balme and Dr. Bechelany. Her PhD work consisted in developing and designing single solid state nanopores to mimic biological channels and to investigate either bio-macromolecules translocation or to functionalize the nanopore to mimic stimuli-dependent ion channels. During her PhD, she was the recipient of a travel grant from the “Chaire Total” for a short-term stay collaboration work with Dr. Dumee group at Deakin University (Australia).
    In January 2017, she started working as a postdoctoral research fellow, at Brown University (Providence (RI), USA), under the guidance of Pr. D. Stein. There, she developed and demonstrated a new kind of ion source capable of efficiently transferring single amino acid ions from liquid into a mass spectrometer. Her results indicate a feasible path to single-molecule protein sequencing through a combination of a single-ion source and mass spectrometry.
    She has co-authored more than 20 papers in peer-reviewed journals [Google scholar], and her work has been presented in 15 international conferences and 8 invited seminars. She has been the recipient of best PhD award from the “pole chimie Balard” in 2017 [LinkedIn] .

Education and professional experience

Research interests

  • Nanopore, Biosensor, Nano-electrochemistry, Material Science

Awards and distinctions

Supervised students and post-doctorants

      • 3 Postdoctoral fellows: Francesca GAMBASSI(2023-2024), Charlotte de BLOIS (2023-2024), Ben SLATER (2021), Javier PEREZ (2019-2021)
      • 4 PhD Students: Xiling SONG (2023-2027), Shaokang JIANG (2021), Zhihao YU (2020-2024), Xin MA (2018-2022)
      • 11 MSc Students: Ximena LUNA GONZALEZ (2024), Leyth SAGLIO (2023), Wouter NIJENHUIS (2023), Thomas MCCLYMONT (2023), Ana Laure CORIA GUTIERREZ (2022), Anna STEVENSON (2020-2021), Narjis EL AMRAOUI (2020), Yutong LI (2020), Andrea FELLONI (2019-2020), Hanna SZAPARY (2017-2018), Marie LEMOUEL (2014)
      • 7 BSc Students: Bilal LAKHRISSI (2023), Paul ROBERT (2022), Marie BILLAUD (2021), Louise DELAURENTI (2020), Gabriel GOUJON (2020), Alban SIMMONOT (2019), Charles BUI (2017-2018), Paulius GAIGALAS (2016), Bastien JAMILLOUX (2015)
      • Xin MA, Master Chemistry and Life Science, PSL, Nov. 2018 – Nov. 2022
      • My-An TRAN, Magistère de Physico-Chimie Moléculaire, Université Paris-Saclay Feb. 2019 – July 2019
      • Andrea FELLONI, M.S. in Nanostructured Materials Engineering, Politecnico di Milano, March 2019 – Feb 2020


Significant publications


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Structure, Orientation and Stability of Lysozyme Confined in Layered Materials Article de journal

Sébastien Balme; Régis Guégan; Jean-Marc Janot; Maguy Jaber; Mathilde Lepoitevin; Philippe Dejardin; Xavier Bourrat; Mikael Motelica-Heino

Soft Matter, 9 (11), p. 3188-3196, 2013.

Controlling Potassium Selectivity and Proton Blocking in a Hybrid Biological/Solid-State Polymer Nanoporous Membrane Article de journal

Sébastien Balme; Fabien Picaud; Sebastian Kraszewski; Philippe Déjardin; Jean Marc Janot; Mathilde Lepoitevin; Jhon Capomanes; Christophe Ramseyer; Franc cois Henn

Nanoscale, 5 (9), p. 3961-3968, 2013.


Controlling Potassium Selectivity and Proton Blocking by Gramicidin A Confined inside Track-Etched Membrane Article de journal

M Lepoitevin; F Picaud; S Kraszewski; JM Janot; F Henn; S Balme


Sodium Insertion-Extraction in the Olivine NaxFePO4 (0$łeq$ X$łeq$ 1) from First-Principles Calculations Article de journal

A Saracibar; J Carrascob; D Saurelb; M Galceranb; B Acebedob; H Anneb; M Lepoitevinb; T Rojoc; Casas M Cabanas


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