2007
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The importance of metal geometry in the recognition of G-quadruplex-DNA by metal-terpyridine complexes Article de journal Hélène Bertrand; David Monchaud; Anne De Cian; Régis Guillot; Jean-Louis Mergny; Marie-Paule Teulade-Fichou Organic & Biomolecular Chemistry, 5 (16), p. 2555–2559, 2007, ISSN: 1477-0520. @article{Bertrand2007,
title = {The importance of metal geometry in the recognition of G-quadruplex-DNA by metal-terpyridine complexes},
author = {H\'{e}l{\`{e}}ne Bertrand and David Monchaud and Anne {De Cian} and R\'{e}gis Guillot and Jean-Louis Mergny and Marie-Paule Teulade-Fichou},
url = {http://dx.doi.org/10.1039/B708635K},
doi = {10.1039/B708635K},
issn = {1477-0520},
year = {2007},
date = {2007-01-01},
journal = {Organic & Biomolecular Chemistry},
volume = {5},
number = {16},
pages = {2555--2559},
publisher = {The Royal Society of Chemistry},
abstract = {A family of terpyridine metallo-organic complexes has been designed and its recognition properties of G-quadruplex-DNA investigated. The series combines easy synthetic access and good affinity\textendashselectivity ratio for quadruplex-DNA. Our study also highlights that the geometry of the metal center strongly governs the ability of the compounds to discriminate quadruplex from duplex-DNA.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
A family of terpyridine metallo-organic complexes has been designed and its recognition properties of G-quadruplex-DNA investigated. The series combines easy synthetic access and good affinity–selectivity ratio for quadruplex-DNA. Our study also highlights that the geometry of the metal center strongly governs the ability of the compounds to discriminate quadruplex from duplex-DNA. |
A platinum–quinacridine hybrid as a G-quadruplex ligand Article de journal Hélène Bertrand; Sophie Bombard; David Monchaud; Marie-Paule Teulade-Fichou JBIC Journal of Biological Inorganic Chemistry, 12 (7), p. 1003–1014, 2007, ISSN: 1432-1327. @article{Bertrand2007a,
title = {A platinum\textendashquinacridine hybrid as a G-quadruplex ligand},
author = {H\'{e}l{\`{e}}ne Bertrand and Sophie Bombard and David Monchaud and Marie-Paule Teulade-Fichou},
url = {https://doi.org/10.1007/s00775-007-0273-3},
doi = {10.1007/s00775-007-0273-3},
issn = {1432-1327},
year = {2007},
date = {2007-01-01},
journal = {JBIC Journal of Biological Inorganic Chemistry},
volume = {12},
number = {7},
pages = {1003--1014},
abstract = {A novel platinum\textendashquinacridine hybrid, comprising a monofunctional Pt moiety and a G-quadruplex ligand (mono-para-quinacridine or MPQ), has been synthesized and shown to interact with quadruplex DNA via a dual noncovalent/covalent binding mode. Denaturing gel electrophoresis was used to separate the various platination products of 22AG (an oligonucleotide that mimics the human telomeric repeat) by Pt-MPQ, and it was shown that two platinated adducts are highly stable quadruplex structures. Dimethylsulfate/piperidine treatment and 3′-exonuclease digestion of the isolated adducts allowed us to precisely determine the platination pattern of 22AG by Pt-MPQ, which displays three main sites G2, G10 and G22. Data presented herein support the hypothesis that Pt-MPQ traps preferentially the antiparallel structure of the 22AG quadruplex. Finally, the kinetics of Pt-MPQ platination using a construct containing both quadruplex DNA and a duplex DNA parts provide the first insights into the Pt-MPQ preference for quadruplex DNA over duplex DNA.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
A novel platinum–quinacridine hybrid, comprising a monofunctional Pt moiety and a G-quadruplex ligand (mono-para-quinacridine or MPQ), has been synthesized and shown to interact with quadruplex DNA via a dual noncovalent/covalent binding mode. Denaturing gel electrophoresis was used to separate the various platination products of 22AG (an oligonucleotide that mimics the human telomeric repeat) by Pt-MPQ, and it was shown that two platinated adducts are highly stable quadruplex structures. Dimethylsulfate/piperidine treatment and 3′-exonuclease digestion of the isolated adducts allowed us to precisely determine the platination pattern of 22AG by Pt-MPQ, which displays three main sites G2, G10 and G22. Data presented herein support the hypothesis that Pt-MPQ traps preferentially the antiparallel structure of the 22AG quadruplex. Finally, the kinetics of Pt-MPQ platination using a construct containing both quadruplex DNA and a duplex DNA parts provide the first insights into the Pt-MPQ preference for quadruplex DNA over duplex DNA. |
Proteomorphous Objects from Abiotic Backbones Article de journal Nicolas Delsuc; Jean-Michel Léger; Stéphane Massip; Ivan Huc Angewandte Chemie International Edition, 46 (1-2), p. 214–217, 2007, ISSN: 14337851, 15213773. @article{delsuc_proteomorphous_2007,
title = {Proteomorphous Objects from Abiotic Backbones},
author = {Nicolas Delsuc and Jean-Michel L\'{e}ger and St\'{e}phane Massip and Ivan Huc},
url = {http://doi.wiley.com/10.1002/anie.200603390},
doi = {10.1002/anie.200603390},
issn = {14337851, 15213773},
year = {2007},
date = {2007-01-01},
urldate = {2018-02-18},
journal = {Angewandte Chemie International Edition},
volume = {46},
number = {1-2},
pages = {214--217},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
|
The Herringbone Helix: A Noncanonical Folding in Aromatic−Aliphatic Peptides Article de journal Nicolas Delsuc; Frédéric Godde; Brice Kauffmann; Jean-Michel Léger; Ivan Huc Journal of the American Chemical Society, 129 (37), p. 11348–11349, 2007, ISSN: 0002-7863, 1520-5126. @article{delsuc_herringbone_2007,
title = {The Herringbone Helix: A Noncanonical Folding in Aromatic−Aliphatic Peptides},
author = {Nicolas Delsuc and Fr\'{e}d\'{e}ric Godde and Brice Kauffmann and Jean-Michel L\'{e}ger and Ivan Huc},
url = {http://pubs.acs.org/doi/abs/10.1021/ja074285s},
doi = {10.1021/ja074285s},
issn = {0002-7863, 1520-5126},
year = {2007},
date = {2007-01-01},
urldate = {2018-02-18},
journal = {Journal of the American Chemical Society},
volume = {129},
number = {37},
pages = {11348--11349},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
|
2006
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Improved Synthesis of Quinacridine Derivatives Article de journal Rémy Lartia; Hélène Bertrand; Marie-Paule Teulade-Fichou Synlett, 2006 (04), p. 610–614, 2006, ISSN: 0936-5214. @article{Lartia2006,
title = {Improved Synthesis of Quinacridine Derivatives},
author = {R\'{e}my Lartia and H\'{e}l{\`{e}}ne Bertrand and Marie-Paule Teulade-Fichou},
doi = {10.1055/s-2006-932465},
issn = {0936-5214},
year = {2006},
date = {2006-01-01},
journal = {Synlett},
volume = {2006},
number = {04},
pages = {610--614},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
|
Vibrational circular dichroism and ab initio structure elucidation of an aromatic foldamer Article de journal Thierry Buffeteau; Laurent Ducasse; Legiso Poniman; Nicolas Delsuc; Ivan Huc Chemical Communications, (25), p. 2714, 2006, ISSN: 1359-7345, 1364-548X. @article{buffeteau_vibrational_2006,
title = {Vibrational circular dichroism and ab initio structure elucidation of an aromatic foldamer},
author = {Thierry Buffeteau and Laurent Ducasse and Legiso Poniman and Nicolas Delsuc and Ivan Huc},
url = {http://xlink.rsc.org/?DOI=b604462j},
doi = {10.1039/b604462j},
issn = {1359-7345, 1364-548X},
year = {2006},
date = {2006-01-01},
urldate = {2018-02-18},
journal = {Chemical Communications},
number = {25},
pages = {2714},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
|
2005
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Probing helix propensity of monomers within a helical oligomer Article de journal Christel Dolain; Jean-Michel Léger; Nicolas Delsuc; Heinz Gornitzka; Ivan Huc Proceedings of the National Academy of Sciences of the United States of America, 102 (45), p. 16146–16151, 2005. @article{dolain_probing_2005,
title = {Probing helix propensity of monomers within a helical oligomer},
author = {Christel Dolain and Jean-Michel L\'{e}ger and Nicolas Delsuc and Heinz Gornitzka and Ivan Huc},
year = {2005},
date = {2005-01-01},
journal = {Proceedings of the National Academy of Sciences of the United States of America},
volume = {102},
number = {45},
pages = {16146--16151},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
|