Generation of Janus alginate hydrogel particles with magnetic anisotropy for cell encapsulation

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TitleGeneration of Janus alginate hydrogel particles with magnetic anisotropy for cell encapsulation
Publication TypeJournal Article
Year of Publication2009
AuthorsZhao, LB, Pan L, Zhang K, Guo SS, Liu W, Wang Y, Chen Y, Zhao XZ, Chan HLW
JournalLab on a Chip
Volume9
Issue20
Pagination2981-2986
ISBN Number1473-0197
Accession NumberISI:000270285600017
Abstract

A microfluidic approach for fabrication of Janus hydrogel particles with magnetic anisotropy is demonstrated. Using this technique, cells and magnetic beads (MBs) can be separately embedded in one hydrogel particle to maintain optical performance, and reduce the contact between cells and magnetic beads (nano-or submicron-particles). Alginate cell capsules prepared by this method can be easily controlled and manipulated by external magnetic fields and require no specific surface modification. Bio-degradability and super-paramagnetic properties of these hydrogel particles were also demonstrated experimentally.

URL<Go to ISI>://000270285600017
DOI10.1039/b907478c
Short TitleGeneration of Janus alginate hydrogel particles with magnetic anisotropy for cell encapsulation
Unit: 
UMR 8640