Yong CHEN

Directeur de recherche (DR1 CNRS)

ENS – Département de chimie
24 rue Lhomond, 75005 Paris

Email: yong.chen@ens.psl.eu
Phone: +33 144322241
Office: E108

Understanding and regulating the natural systems at cellular levels is of particular interesting for disease modeling, drug screening, diagnosis and regenerative medicine. By developing consistently artificial basement membranes, microfluidic and pluripotent stem cell technologies, advanced in-vitro models of human tissues/organoids can be created, which mimic our sophisticated in-vivo systems.

Short bio

He received a B.S. degree in condensed matter physics from Wuhan University (1982) and  both M.S. and Ph.D. degrees from the University of Montpelier (1983 and 1986). After spent three years at the Scuola Normale Superiorie di Pisa and Peking University, he joined the Centre National de Recherche Scientifique (CNRS) as Chargé de Recherche (1st class) in 1990 to work at the Laboratoire  de Microstructures et de Microélectronique (L2M). In 1998, he became a Directeur de Recherche (2nd class) of CNRS. In 2003, he moved to the Ecole Normale Supérieure (ENS) as Professor and he is now Directeur de Recherche (1st class) of CNRS and head of the ENS team for microfluidics. In the past, he also served as Adjunct Professor at the Institute for Integrated Cell-Material Sciences (iCeMS) of Kyoto University, Changjiang Chair Professor of Peking University, Distinguished Chair Professor of Hong Kong Polytechnic University and Guess professor of Jianghan University.

Research interests

He has been worked in different fields, including semiconductor quantum heterostructures, photonic crystals, scanning near field optical microscopy, magnetic nanostructures, synchrotron based X-ray lithography, thermal and UV nanoimprint lithography, microfluidics, etc. His current interests are mainly in the field of biomedical research and applications such as cancer diagnosis and stem cell devices for in-vitro modeling of cardiac,  neural and alveolar systems.

He has contributed to more than 500 scientific publications (peer-reviewed journals, book chapters and proceeding articles) and a large number of European and national research projects/networks. He is member of several international or national committees and reviewer of a number of journals. In total, he has supervised more than 50 Ph.D and post-doc studies.

Publications

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2007

Patterning of hydrophilic micro arrays with superhydrophobic surrounding zones Article de journal

SS Guo; MH Sun; J Shi; YJ Liu; WH Huang; C Combellas; Y Chen

Microelectronic engineering, 84 (5-8), p. 1673–1676, 2007.

Reactive ion etching of high optical quality GaN/ sapphire photonic crystal slab using CH 4--H 2 chemistry Article de journal

S Bouchoule; S Boubanga-Tombet; L Le Gratiet; M Le Vassor d’Yerville; J Torres; Y Chen; D Coquillat

Journal of applied physics, 101 (4), p. 043103, 2007.

2006

Coupling of electrochemistry and fluorescence microscopy at indium tin oxide microelectrodes for the analysis of single exocytotic events Article de journal

C Amatore; S Arbault; Y Chen; C Crozatier; F Lemaître; Y Verchier

Angewandte Chemie - International Edition, 45 (24), p. 4000–4003, 2006.

Tri-layer soft UV imprint lithography and fabrication of high density pillars Article de journal

J Shi; C Peroz; D Peyrade; J Salari; M Belotti; WH Huang; Y Chen

Microelectronic engineering, 83 (4-9), p. 1664–1668, 2006.

Toward a comparative study of protein crystallization in microfluidic chambers using vapor diffusion and batch techniques Article de journal

M Lounaci; P Rigolet; Velve G Casquillas; HW Huang; Y Chen

Microelectronic engineering, 83 (4-9), p. 1673–1676, 2006.

Strongly enhanced third order nonlinear response of periodically nano-structured Silicon on Insulator (SOI) measured by reflection Z-scan with femtosecond pulses Article de journal

A Petris; F Pettazzi; E Fazio; C Peroz; Y Chen; VI Vlad; M Bertolotti

Journal of Optoelectronics and Advanced Materials, 8 (4), p. 1377, 2006.

Reversible assembling of microfluidic devices by aspiration Article de journal

M Le Berre; C Crozatier; Velve G Casquillas; Y Chen

Microelectronic Engineering, 83 (4-9), p. 1284–1287, 2006.

Response of super-paramagnetic beads in microfluidic devices with integrated magnetic micro-columns Article de journal

SS Guo; CC Zuo; WH Huang; C Peroz; Y Chen

Microelectronic engineering, 83 (4-9), p. 1655–1659, 2006.

Multi-colour micro-contact printing based on microfluidic network inking Article de journal

C Crozatier; M Le Berre; Y Chen

Microelectronic engineering, 83 (4-9), p. 910–913, 2006.

Microfluidic dye laser intracavity absorption Article de journal

JC Galas; C Peroz; Q Kou; Y Chen

Applied physics letters, 89 (22), p. 224101, 2006.

Focused ion beam sculpted membranes for nanoscience tooling Article de journal

A-L Biance; J Gierak; E Bourhis; A Madouri; X Lafosse; G Patriarche; G Oukhaled; C Ulysse; J-C Galas; Y Chen; others

Microelectronic engineering, 83 (4-9), p. 1474–1477, 2006.

Compact dye laser on a chip fabricated by ultraviolet nanoimprint lithography Article de journal

Ch Peroz; JC Galas; L Le Gratiet; Y Chen; J Shi

Applied physics letters, 89 (24), p. 243109, 2006.

Collinear dual-color laser emission from a microfluidic dye laser Article de journal

Q Kou; I Yesilyurt; Y Chen

Applied physics letters, 88 (9), p. 091101, 2006.

Thermal radiation scanning tunnelling microscopy Article de journal

Y De Wilde; F Formanek; R Carminati; B Gralak; P -A Lemoine; K Joulain; J -P Mulet; Y Chen; J -J Greffet

Nature, 444 (7120), p. 740–743, 2006.

Synthesis of water-soluble 2-alkylcyclodextrin-C60 conjugates and their inclusion complexation in aqueous solution Article de journal

Y Chen; Y Wang; A Rassat; P Sinaÿ; Y Zhao; Y Zhang

Tetrahedron, 62 (9), p. 2045–2049, 2006.

Strong enhancement of Er3+ emission at room temperature in silicon-on-insulator photonic crystal waveguides Article de journal

M Galli; A Politi; M Belotti; D Gerace; M Liscidini; M Patrini; L C Andreani; M Miritello; A Irrera; F Priolo; Y Chen

Applied Physics Letters, 88 (25), 2006.

The direct, in situ, measurement of the flow velocity inside microfluidic devices via electrochemical coupling between two parallel microband electrodes Article de journal

C Amatore; Y Chen; C Sella; L Thouin

Houille Blanche, (2), p. 60–64, 2006.

2005

Characterization of pneumatically activated microvalves by measuring electrical conductance Article de journal

J-C Galas; V Studer; Y Chen

Microelectronic engineering, 78 , p. 112–117, 2005.

Single-mode versus multimode behavior in silicon photonic crystal waveguides measured by attenuated total reflectance Article de journal

M Galli; D Bajoni; M Patrini; G Guizzetti; D Gerace; LC Andreani; M Belotti; Y Chen

Physical Review B, 72 (12), p. 125322, 2005.

Microfluidic tunable dye laser with integrated mixer and ring resonator Article de journal

JC Galas; J Torres; M Belotti; Q Kou; Y Chen

Applied Physics Letters, 86 (26), p. 264101, 2005.

In situ bio-functionalization and cell adhesion in microfluidic devices Article de journal

ZL Zhang; C Crozatier; M Le Berre; Y Chen

Microelectronic Engineering, 78 , p. 556–562, 2005.

Enhanced third harmonic reflection and diffraction in Silicon on Insulator photonic waveguides Article de journal

C Comaschi; G Vecchi; AM Malvezzi; M Patrini; G Guizzetti; M Liscidini; LC Andreani; D Peyrade; Y Chen

Applied Physics B, 81 (2-3), p. 305–311, 2005.

Enhanced UV imprint ability with a tri-layer stamp configuration Article de journal

E Roy; Y Kanamori; M Belotti; Y Chen

Microelectronic engineering, 78 , p. 689–694, 2005.

Electrocapillary force actuation of microfluidic elements Article de journal

M Le Berre; Y Chen; C Crozatier; ZL Zhang

Microelectronic engineering, 78 , p. 93–99, 2005.

Enhanced third harmonic reflection and diffraction in Silicon on Insulator photonic waveguides Article de journal

C Comaschi; G Vecchi; A M Malvezzi; M Patrini; G Guizzetti; M Liscidini; L C Andreani; D Peyrade; Y Chen

Applied Physics B: Lasers and Optics, 81 (2-3), p. 305–311, 2005.

Regioselective one-step synthesis of hexahydroxy permethylated β-cyclodextrin and unambiguous NMR analysis Article de journal

Y Chen; J G Huber; Y Zhang; P Sinaÿ

Comptes Rendus Chimie, 8 (1), p. 27–30, 2005.

Single-mode versus multimode behavior in silicon photonic crystal waveguides measured by attenuated total reflectance Article de journal

M Galli; D Bajoni; M Patrini; G Guizzetti; D Gerace; L C Andreani; M Belotti; Y Chen

Physical Review B - Condensed Matter and Materials Physics, 72 (12), 2005.

Antireflection sub-wavelength gratings fabricated by spin-coating replication Article de journal

Y Kanamori; E Roy; Y Chen

Microelectronic Engineering, 78 , p. 287–293, 2005.

2004

Giant second-harmonic generation in a one-dimensional GaN photonic crystal Article de journal

Jeremi Torres; Dominique Coquillat; Rene Legros; Jean-Paul Lascaray; Frederic Teppe; Denis Scalbert; D Peyrade; Y Chen; Olivier Briot; Le Vassor M d’Yerville; others

Physical Review B, 69 (8), p. 085105, 2004.

On-chip optical components and microfluidic systems Article de journal

Q Kou; I Yesilyurt; V Studer; M Belotti; E Cambril; Y Chen

Microelectronic engineering, 73 , p. 876–880, 2004.

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