Jean-Maurice MALLET

Directeur de recherche CNRS

ENS – Département de chimie
24 rue Lhomond, 75005 Paris
Phone: +33 144323390
Office: E048

Short bio

Education and professional experience

1980 Student at Ecole Normale Supérieure (45 rue d’Ulm, Paris), 1980 S,
1983 Agregation de chimie
1983-85 Chemistry and physics teacher at Tevfik Fikret lise at Ankara, Turkey
1985-1988 PhD thesis at Université Paris VI (supervisor: Prof. Marc Julia)
“Elimination reaction in terpenic serie, Taft constants of phosphoric ester. New methods for the preparation of tert butyl ethers and esters.
1985-1987 Teaching assistant /Agrégé préparateur à l’ENS
1987-now CNRS researcher:
Chargé de Recherche CNRS (URA 1686/ UMR 8642) (1987-2001)
Directeur de Recherche CNRS (2001, 2nd class) (2012, 1st class)

Research interests

  • Chemical biology
  • Synthetic oligosaccharides, and conjugates: thioglycosides -Synthesic oligosaccharides and glycoconjugates, multivalent systems
  • Peptides and glycopeptides, mimotopes, antigenic peptides
  • Bacterial metabolites in gut inflammation
  • Fluorescent and fluorogenic probes for subcellular imaging
  • Functional Micro and nanoparticles: nanogels, gold NP, microdroplet

Supervised students and post-doctorants

  • PhD Thesis
    • Pascal Matton  (2014-2017) Codir J Fattaccioli
    • Agathe Peyrottes (2016-2019)   Codir   JP Grill
    • Roxane Ornstein  (2016-2019)
    • Antonio Mazoleni (2017-2020)   Codir A M Papini, univ Florence
    • Agathe Brudo (2018-2021) codir  C Mansuy
    • Yutong Li (2020-2023)

Last publications ( 2018-2021)

see more publications from pubmed site

  1. Distinct postprandial bile acids responses to a high-calorie diet in Men volunteers underscore metabolically healthy and unhealthy phenotypes Antonin Lamaziere, Dominique Rainteau, Pukar Kc, Lydie Humbert, Emilie Gauliard, Elena Visibelli, Farid Ichou, Maharajah Ponnaiah, Nadine Bouby, Joe-Elie Salem, Katja Schuerer, William Saurin, Jean-Maurice Mallet, Maryse Guerin, Philippe Lesnik
    Nutrients 2020, 12, 3545; doi:10.3390/nu12113545
  2. Anti-inflammatory Effects of N-Acyl Homoserine Lactones Analogues on Eukaryotic Cells Agathe Peyrottes, Loïc Brot, Garance Coquant, Dominique Rainteau, Philippe Seksik, Jean-Pierre Grill, Jean-Maurice Mallet J. Mol. Sci. 2020, 21(24), 9448;
  3. Fluorogenic protein probes with red or near-infrared emission for genetically targeted live-cell imaging;
    Sylvestre P. J. T. Bachollet,; Cyril Addi, Nicolas Pietrancosta; Jean-Maurice Mallet, Blaise Dumat
    Chemistry 2020 10.1002/chem.2020029
  4. Hyper-glucosylated adhesin derived peptides as antigenic probes in multiple sclerosis: structure optimisation and immunological evaluationAntonio Mazzoleni, Feliciana Real-Fernandez, Maud Larregola , Olivier Lequin , Anna Maria Papini , Jean-Maurice Mallet* , Paolo Rovero* J Pept. Sci, 2020, DOI:10.1002/psc.3281
  5. A microenvironment-sensitive coumarin-labeled peptide for the assessment of lipid-peptide interactions.Francisco Mura, Daniel Zúñiga-Núñez, Solange Lavielle, Jean-Maurice Mallet, Pascal Matton, Pablo Barrías, Denis Fuentealba, and Alexis Aspée, Dye and pigments,176, 2020,108234. DOI:10.1016/j.dyepig.2020.108234
  6. Mannose-coated fluorescent lipid particles to decipher glycoreceptor-induced phagocytosis Dumat, L. Montel, L. Pinon, P. Matton, L. Cattiaux, J. Fattaccioli, J.-M. Mallet  ACS Applied Bio Materials, 2019, doi 10.1021/acsabm.9b00793,
  7. Glycoreplica peptides to investigate molecular mechanisms of immune-mediated physiological versus pathological conditions A Mazzoleni, P Rovero, J-M Mallet, A M Papini Arch Biochem Biophys, 2019; 663,44-53. doi: 10.1016/
  8. Inter-kingdom effect on epithelial cells of the N-Acyl homoserine lactone 3-oxo-C12:2, a major quorum-sensing molecule from gut microbiota -C Landman, J-P Grill, J- M Mallet, P Marteau, L Humbert, Eric Le Balc’h, M-A Maubert, K Perez, W Chaara, L Brot, L Beaugerie, H Sokol, S Thenet, D Rainteau, P Seksik, E Quévrain PLOS ONE, 2018 10.1371/journal.pone.0202587
  9. New branched amino acids for very high affinity dendrimeric DC-sign ligands L Cattiaux, V Porkolab; F Fieschi, J-M Mallet, Bioorg Med Chem. 2018, 26, 1006-1015
  10. Redox-controlled fluorescence modulation in rhodamine derivatives; M Čížková, L Cattiaux, J-M Mallet, E Labbé, O Buriez, Electrochimica Acta 260 (2018) 589-597
  11. A diarylethene-based photoswitchable chelator for reversible release and capture of calcium ions in aqueous media -N Dozova, G Pousse, B Barnych, J-M Mallet, J Cossy, B Valeur, P Plaza J Photochem Photobiol A: Chemistry; 2018, 10.1016/j.jphotochem.2018.04.029
  12. Redox switchable rhodamine-ferrocene dyad: exploring imaging possibilities in cells M Čížková, L Cattiaux, J Pandard, M Guille-Collignon, F Lemaître, Jérôme Delacotte, J-M Mallet, E Labbé, O Buriez, Electrochem Commun 2018, 10.1016/j.elecom.2018.10.009