Bio-inorganic Chemistry

@article{buffeteau_vibrational_2006,
title = {Vibrational circular dichroism and ab initio structure elucidation of an aromatic foldamer},
author = {Thierry Buffeteau and Laurent Ducasse and Legiso Poniman and Nicolas Delsuc and Ivan Huc},
url = {http://xlink.rsc.org/?DOI=b604462j},
doi = {10.1039/b604462j},
issn = {1359-7345, 1364-548X},
year = {2006},
date = {2006-01-01},
urldate = {2018-02-18},
journal = {Chemical Communications},
number = {25},
pages = {2714},
keywords = {},
pubstate = {published},
tppubtype = {article}
}

@article{dolain_probing_2005,
title = {Probing helix propensity of monomers within a helical oligomer},
author = {Christel Dolain and Jean-Michel L\'{e}ger and Nicolas Delsuc and Heinz Gornitzka and Ivan Huc},
year = {2005},
date = {2005-01-01},
journal = {Proceedings of the National Academy of Sciences of the United States of America},
volume = {102},
number = {45},
pages = {16146--16151},
keywords = {},
pubstate = {published},
tppubtype = {article}
}

@article{doi:10.1021/acs.inorgchem.0c03718,
title = {A di-Copper Peptidyl Complex Mimics the Activity of Catalase, a Key Antioxidant Metalloenzyme},
author = {Koudedja Coulibaly and Marion Thauvin and Adyn Melenbacher and Clara Testard and Evangelia Trigoni and Amandine Vincent and Martin J Stillman and Sophie Vriz and Clotilde Policar and Nicolas Delsuc},
url = {https://doi.org/10.1021/acs.inorgchem.0c03718},
doi = {10.1021/acs.inorgchem.0c03718},
year = {0000},
date = {0000-01-01},
journal = {Inorganic Chemistry},
volume = {0},
number = {0},
pages = {null},
abstract = {Catalases (CAT) are antioxidant metalloenzymes necessary for life in oxygen-metabolizing cells to regulate H2O2 concentration by accelerating its dismutation. Many physiopathological situations are associated with oxidative stress resulting from H2O2 overproduction, during which antioxidant defenses are overwhelmed. We have used a combinatorial approach associated with an activity-based screening to discover a first peptidyl di-copper complex mimicking CAT. The complex was studied in detail and characterized for its CAT activity both in solutions and in cells using different analytical methods. The complex exhibited CAT activity in solutions and, more interestingly, on HyPer HeLa cells that possess a genetically encoded ratiometric fluorescent sensors of H2O2. These results highlight the efficiency of a combinatorial approach for the discovery of peptidyl complexes that exhibit catalytic activity.},
note = {PMID: 34109781},
keywords = {},
pubstate = {published},
tppubtype = {article}
}