Asymmetrical stress generated by the erythrocyte lipid flippase triggers multiple bud formation on the surface of spherical giant liposomes

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TitreAsymmetrical stress generated by the erythrocyte lipid flippase triggers multiple bud formation on the surface of spherical giant liposomes
Type de publicationJournal Article
Nouvelles publications2010
AuteursEzanno P, Cribier S, Devaux PF
JournalEuropean Biophysics Journal with Biophysics Letters
Volume39
Fascicule8
Pagination1277-1280
Année de publicationJul
Numéro0175-7571
Accession NumberISI:000279194500015
Résumé

Proteo-giant liposomes were electroformed from a mixture of lecithin vesicles and inside-out vesicles from erythrocytes. After addition of Mg-ATP in the vicinity of the proteo-giant liposomes, small buds appeared on the liposome surfaces, which-via an increase in lipids in the outer monolayer-demonstrated the active transport of lipids from the inner to the outer monolayer, indicating flippase activity.

URL<Go to ISI>://000279194500015
DOI10.1007/s00249-009-0557-3
Importer un fichierAsymmetrical stress generated by the erythrocyte lipid flippase triggers multiple bud formation on the surface of spherical giant liposomes
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