Bio - Nicolas Delsuc

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Nicolas Delsuc


Chargé de Recherche CNRS

ENS, Department of Chemistry, 24 rue Lhomond

Metals in Biology - Inorganic Cellular Chemistry


  1. Bioinspired superoxide-dismutase mimics: The effects of functionalization with cationic polyarginine peptides.
    Ching HY, Kenkel I, Delsuc N, Mathieu E, Ivanović-Burmazović I, Policar C.
    J Inorg Biochem. 2016 Jan 29. pii: S0162-0134(16)30024-1. doi: 10.1016/j.jinorgbio.2016.01.025.
  2. Photophysical properties of single core multimodal probe for imaging (SCoMPI) in a membrane model and in cells.
    Hostachy S, Swiecicki JM, Sandt C, Delsuc N, Policar C.
    Dalton Trans. 2016 Feb 21;45(7):2791-5. doi: 10.1039/c5dt03819g.
  3. Synthesis, characterization and biological activity of Cu(II), Zn(II) and Re(I) complexes derived from S-benzyldithiocarbazate and 3-acetylcoumarin.
    Low ML, Paulus G, Dorlet P, Guillot R, Rosli R, Delsuc N, Crouse KA, Policar C.
    Biometals. 2015 Jun;28(3):553-66. doi: 10.1007/s10534-015-9831-2.
  4. An easy-to-detect nona-arginine peptide for epidermal targeting.
    Clède S, Delsuc N, Laugel C, Lambert F, Sandt C, Baillet-Guffroy A, Policar C.
    Chem Commun (Camb). 2015 Feb 14;51(13):2687-9. doi: 10.1039/c4cc08737b.
  5. Conjugation of a new series of dithiocarbazate Schiff base Copper(II) complexes with vectors selected to enhance antibacterial activity.
    Low ML, Maigre L, Dorlet P, Guillot R, Pagès JM, Crouse KA, Policar C, Delsuc N.
    Bioconjug Chem. 2014 Dec 17;25(12):2269-84. doi: 10.1021/bc5004907.
  6. 3-Substituted prolines: from synthesis to structural applications, from peptides to foldamers.
    Mothes C, Caumes C, Guez A, Boullet H, Gendrineau T, Darses S, Delsuc N, Moumné R, Oswald B, Lequin O, Karoyan P.
    Molecules. 2013 Feb 19;18(2):2307-27. doi: 10.3390/molecules18022307. .
  7. Synchrotron radiation FTIR detection of a metal-carbonyl tamoxifen analog. Correlation with luminescence microscopy to study its subcellular distribution.
    Clède S, Lambert F, Sandt C, Gueroui Z, Delsuc N, Dumas P, Vessières A, Policar C.
    Biotechnol Adv. 2013 May-Jun;31(3):393-5. doi: 10.1016/j.biotechadv.2012.01.023.
  8. Relative helix-helix conformations in branched aromatic oligoamide foldamers.
    Delsuc N, Massip S, Léger JM, Kauffmann B, Huc I.
    J Am Chem Soc. 2011 Mar 9;133(9):3165-72. doi: 10.1021/ja110677a.
  9. Cascading transformations within a dynamic self-assembled system.
    Campbell VE, de Hatten X, Delsuc N, Kauffmann B, Huc I, Nitschke JR.
    Nat Chem. 2010 Aug;2(8):684-7. doi: 10.1038/nchem.693.
  10. Interplay of interactions governing the dynamic conversions of acyclic and macrocyclic helicates.
    Campbell VE, de Hatten X, Delsuc N, Kauffmann B, Huc I, Nitschke JR.
    Chemistry. 2009 Jun 15;15(25):6138-42. doi: 10.1002/chem.200900693.
  11. Helical aromatic oligoamide foldamers as organizational scaffolds for photoinduced charge transfer.
    Wolffs M, Delsuc N, Veldman D, Nguyên VA, Williams RM, Meskers SC, Janssen RA, Huc I, Schenning AP.
    J Am Chem Soc. 2009 Apr 8;131(13):4819-29. doi: 10.1021/ja809367u.
  12. Kinetics of helix-handedness inversion: folding and unfolding in aromatic amide oligomers.
    Delsuc N, Kawanami T, Lefeuvre J, Shundo A, Ihara H, Takafuji M, Huc I.
    Chemphyschem. 2008 Sep 15;9(13):1882-90. doi: 10.1002/cphc.200800310.
  13. Metal-directed dynamic formation of tertiary structure in foldamer assemblies: orienting helices at an angle.
    Delsuc N, Hutin M, Campbell VE, Kauffmann B, Nitschke JR, Huc I.
    Chemistry. 2008;14(24):7140-3. doi: 10.1002/chem.200800988.
  14. The herringbone helix: a noncanonical folding in aromatic-aliphatic peptides.
    Delsuc N, Godde F, Kauffmann B, Léger JM, Huc I.
    J Am Chem Soc. 2007 Sep 19;129(37):11348-9.
  15. Proteomorphous objects from abiotic backbones.
    Delsuc N, Léger JM, Massip S, Huc I.
    Angew Chem Int Ed Engl. 2007;46(1-2):214-7.
  16. Vibrational circular dichroism and ab initio structure elucidation of an aromatic foldamer.
    Buffeteau T, Ducasse L, Poniman L, Delsuc N, Huc I.
    Chem Commun (Camb). 2006 Jul 5;(25):2714-6.
  17. Probing helix propensity of monomers within a helical oligomer.
    Dolain C, Léger JM, Delsuc N, Gornitzka H, Huc I.
    Proc Natl Acad Sci U S A. 2005 Nov 8;102(45):16146-51.