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Connecting dysbiosis, bile-acid dysmetabolism and gut inflammation in inflammatory bowel diseases

Gut microbiota metabolises bile acids (BA). As dysbiosis has been reported in inflammatory bowel diseases (IBD), we aim to investigate the impact of IBD associated dysbiosis on BA metabolism and its influence on the epithelial cell inflammation response.

Connecting dysbiosis, bile-acid dysmetabolism and gut inflammation in inflammatory bowel diseases

Gut microbiota metabolises bile acids (BA). As dysbiosis has been reported in inflammatory bowel diseases (IBD), we aim to investigate the impact of IBD associated dysbiosis on BA metabolism and its influence on the epithelial cell inflammation response.

Calcium Rubies: A Family of Red-Emitting Functionalizable Indicators

We designed Calcium Rubies, a family of functionalizable BAPTA-based red-fluorescent calcium (Ca2+) indicators as new tools for biological Ca2+ imaging.

NMR Crystallography:Disentangling Crystallographic Inequivalence and Crystallographic Forms of L-Arginine by One- and Two-Dimensional Solid-State NMR Spectroscopy

Overlapping 13C or 15N solid-state NMR spectra from crystallographically different forms of L-arginine hydrochloride can be separated by exploiting differential proton T1 relaxation in conjunction with cross polarization.

 

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Mapping molecules inside cells is a contemporary challenge that requires both high sensitivity and sub-micrometric resolution. IR-spectroscopy is valuable for chemical imaging.